In 1772, William Heberden described ‘a disorder of the breast marked with strong and peculiar symptoms… [with a] sense of strangling and anxiety’. Individuals affected are ‘seized while they are ...

Objective D-dimer might serve as a marker of thrombogenesis and a hypercoagulable state following plaque rupture. Few studies explore the association between baseline D-dimer levels and the incidence ...

Background Resistance training (RT) for improving muscular strength is a fundamental part of the exercise component in Cardiac Rehabilitation (CR) protocols for post-open-heart surgeries. Although ...

Objective Decreased kidney function increases cardiovascular risk and predicts poor survival. Estimated glomerular filtration rate (eGFR) by creatinine may theoretically be less accurate in the ...

Introduction The European Society of Cardiology (ESC) guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death recommend that subcutaneous ...

The management of atrial fibrillation (AF) has focused on anticoagulation, rhythm control and ventricular rate control. Recently, a fourth pillar of AF management has been incorporated recognising the ...

Methods Ten athletes were referred from external pre-participation screening. All exhibited prominent deep symmetrical T wave inversion in the inferolateral leads (figure 1). All had negative family ...

Background Both the insulin secretion and insulin resistance in Type 2 diabetes (T2D) are amenable to pharmacological intervention. promote insulin secretion, causes weight loss and is an important ...

Results A total of 92 HCM patients were identified, with median follow up period 52 months, median age 56 years (range 15–86), and male sex in 64%. Twelve patients had an implantable cardioverter ...

Results The median percentage decrease in platelet count was 37.8% [IQR: 28.8–48.4], resulting in moderate (<100*109/L) and severe (<50*109/L) thrombocytopenia in 28.8% and 4.2% of patients, ...

Background Anomalous aortic origin of a coronary artery (AAOCA) is a congenital abnormality of the origin or course of coronary artery. The clinical manifestations of coronary artery anomalies vary in ...

Objective Ascorbic acid has been reported to promote the differentiation of embryonic stem cells (ESCs) into cardiomyocytes (CMs). However, appropriate culture protocols are needed to improve the ...