We later further expanded the QTY code to other integral membrane proteins including cytokine receptors. QTY code is a simple tool for designs of water-soluble membrane proteins based on the ...

It is known that serine is a polar amino acid with a hydroxyl group (-OH) in its side chain, allowing it to form hydrogen bonds and participate in polar interactions, while leucine is a non-polar ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Clostridium thermocellum, a cellulolytic thermophilic anaerobe, is considered by many to be a prime candidate for the realization of consolidated bioprocessing (CBP) and is known as an industry ...

Long MD simulations are carried out using a detailed all-atom force field to investigate the effect of pH or, equivalently, degree of ionization α – (= 0, 50, 100%) and degree of polymerization N (= ...