Notably, we found that NOX2 plays a significant role in increasing the activity of a gene called PITX2, which is linked to changes in the heart's electrical function.

Obesity is linked to atrial fibrillation, an irregular heart rhythm that increases the risk of stroke, heart failure, and premature death.

Taken together, and owing to the fact that NOX2 is highly expressed in infiltrating immune cells, these data suggest novel roles for NOX2 in cancer immunology, which should be further explored.

This study presents evidence that dextran sulfate sodium (DSS)-induced colitis exacerbates periodontitis through the activation of the NADPH oxidase 2 (NOX2)/reactive oxygen species (ROS) axis in ...

Celros Biotech Co. Ltd. has synthesized cytochrome b-245 heavy chain (CYBB; NOX2) and NADPH oxidase 4 (NOX4) inhibitors reported to be useful for the treatment of atherosclerosis, Alzheimer’s disease, ...

Consumption of a high fat diet may be activating a response in the heart that is causing destructive growth and lead to greater risk of heart attacks, according to new research.

These compounds inhibit the enzyme Nox2, part of a family of enzymes responsible for producing reactive oxygen species.

Celros Biotech Co. Ltd. has described cytochrome b-245 heavy chain (CYBB; NOX2) and NADPH oxidase 4 (NOX4) inhibitors reported to be useful for the treatment of neuroinflammatory disorders.