For patients with unexplained multisystem symptoms, getting answers can mean navigating competing criteria and conflicting ...

The interaction between mast cells and other immune cells at sites of allergic responses has been largely unexplored. A research group at the MPI of Immunobiology and Epigenetics used specialized ...

Mast cells are long-lived, tissue-resident immune cells whose responses are shaped by their anatomical niches. Despite their ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown that in mice mast cells function as a sensor ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

First-in-class bispecific antibody designed for mast cell elimination without the safety issues associated with current KIT therapeuticsPhase 1 ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow. It mainly occurs in older individuals and represents about 20 ...

Mast cells are immune cells that responds to different pathogens, such as bacteria and parasites. In response to these pathogens, mast cells release different chemicals, such as histamine and heparin, ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, ...