NFL Combine has come to a close, as many draft-hopeful prospects cemented their draft stock over the weekend headlined by a ...

The Detroit Lions will square off with the San Francisco 49ers on Monday Night Football in Week 17 of the NFL season at Levi’s Stadium, scheduled to start at 8:15 p.m. EST. All week, questions ...

While the San Francisco 49ers injury problems stack up and their list of players on IR balloons to 16, they actually got some good news on running back Isaac Guerendo leading up to their Week 17 ...

SANTA CLARA, Calif. -- After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to play Monday night against the Detroit Lions. Guerendo ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN's Adam Schefter. Guerendo has been limited in practice this week ...

That includes the development of San Francisco's young players, such as rising rookie running back Isaac Guerendo. The 24-year-old missed last week's game against the Miami Dolphins due to ...

Guerendo (foot/hamstring) practiced in a limited capacity Friday, Nick Wagoner of ESPN.com reports. Guerendo now has managed back-to-back capped sessions to kick off Week 17 prep as he looks to ...

Injuries have decimated the reigning NFC champs. Isaac Guerendo, however, provided a promising update. The alternate running back appears to be on his way back, per 49ers reporter Nick Wagoner of ...

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports. Guerendo picked up foot and hamstring injuries in Week 15 ...

San Francisco 49ers running back Isaac Guerendo. / Bob Kupbens-Imagn Images The San Francisco 49ers are already down Jordan Mason and Christian McCaffrey in their backfield (both are on injured ...