PAH is a rare condition in children, but is often fatal if left untreated, and protocols for pediatric patients have not been ...

Mosliciguat is under clinical development by Bayer and currently in Phase I for Kidney Disease (Nephropathy). According to GlobalData, Phase I drugs for Kidney Disease (Nephropathy) have a 71% phase ...

This phase 1–2, randomised, double-blind, placebo-controlled trial enrolled 130 patients aged 18 or older with confirmed ...

Owing to these mechanisms of action, Ibsrela is a first-in-class IBS-C med, with the other four approved therapies classified as guanylate cyclase-C [GCC] agonists. The latter drugs promote the ...

Its primary products include a portfolio of soluble guanylate cyclase (sGC) stimulators aimed at generating revenues and advancing its strategic initiatives. YTD Price Performance: 5.37% Average ...

CAS Key Laboratory of Environmental and Applied Microbiology, Environmental Microbiology Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ...

cGMP plays a central role in cardiovascular regulation in health and disease. It is synthesized by NO or natriuretic peptide activated cyclases and hydrolyzed to 5′GMP by select members of the PDEs ...