PAH is a rare condition in children, but is often fatal if left untreated, and protocols for pediatric patients have not been ...

Ironwood Pharmaceuticals, Inc. (NASDAQ:IRWD – Get Free Report) has been given an average rating of “Moderate Buy” by the six research firms that are covering the company, MarketBeat.com reports. Three ...

a soluble guanylate cyclase activator and an off-the-shelf, virus-specific T cell therapy. These advances herald new hope for people with kidney disease. Progression of chronic kidney disease to ...

Mosliciguat is under clinical development by Bayer and currently in Phase I for Kidney Disease (Nephropathy). According to GlobalData, Phase I drugs for Kidney Disease (Nephropathy) have a 71% phase ...

A new study published in the Journal of American Medical Association showed that individuals with heart failure with ...

This phase 1–2, randomised, double-blind, placebo-controlled trial enrolled 130 patients aged 18 or older with confirmed ...

Owing to these mechanisms of action, Ibsrela is a first-in-class IBS-C med, with the other four approved therapies classified as guanylate cyclase-C [GCC] agonists. The latter drugs promote the ...

Most additives are only permitted to be used in certain foods and are subject to specific quantitative limits, so it is important to note this list should be used in conjunction with the appropriate ...

Its primary products include a portfolio of soluble guanylate cyclase (sGC) stimulators aimed at generating revenues and advancing its strategic initiatives. YTD Price Performance: 5.37% Average ...

CAS Key Laboratory of Environmental and Applied Microbiology, Environmental Microbiology Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ...

This study presents valuable findings on an unresolved question of cerebellar physiology: Do synapses between Purkinje cells and granule cells, made by the ascending part of the granule cells' axon, ...

cGMP plays a central role in cardiovascular regulation in health and disease. It is synthesized by NO or natriuretic peptide activated cyclases and hydrolyzed to 5′GMP by select members of the PDEs ...