Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...

Researchers have developed a novel delivery system for sending CRISPR reagents to brain cells, where it performs its gene ...

X-linked chronic granulomatous disease (X-CGD) is a rare genetic disorder characterized by high susceptibility to infections that results from genetic mutations in the cytochrome b-245 beta chain ...

In a phase 2 trial, a gene therapy reduced angioedema attacks, which could significantly change the quality of life for ...

Spanish biotech Integra Therapeutics has upped its arsenal of gene editing tools by licensing Caszyme’s Cas12I nucleases, the ...

"Our results demonstrate how the improved capabilities of engineered CRISPR-Cas9 enzymes can be beneficial, and together motivate additional studies using base editors to correct other mutations ...

Sending the manual to build the CAS9 enzyme for gene editing The new study describes the use of the LNP technology for Cas9 mRNA delivery to treat central nervous system genetic diseases in utero.

Crispr/Cas9 works by having Crispr (pieces of DNA sequences) guide Cas9 (an enzyme that can cut and edit DNA) to edit, alter, or repair genes. We think Crispr Therapeutics' proprietary technology has ...