A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

The pathway by which blood cells release the important signalling lipid, sphingosine-1-phosphate (S1P), has now been discovered. They showed that the membrane protein Mfsd2b is responsible for ...

The mevalonate (MVA) pathway is an essential metabolic pathway that is affected by many oncogenic signalling pathways. This Review discusses the opportunity to immediately target the MVA pathway ...

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of ...

Discovery of cross-species signaling pathway unlocks mysteries around parasite immunity and development Ticks recognize a cytokine from infected mammalian blood, triggering a defense against Lyme ...