A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

The pathway by which blood cells release the important signalling lipid, sphingosine-1-phosphate (S1P), has now been discovered. They showed that the membrane protein Mfsd2b is responsible for ...

These activated signalling cascades in turn deregulate the expression 8, 9 and/or the activity of enzymes in key metabolic pathways 10, including the mevalonate (MVA) pathway (Figs 1, 2).

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Complex organisms rely on a fairly small number of signalling pathways to regulate all of their responses to developmental and environmental cues. Traditionally, it has been assumed that ...

Research has identified the first inter-species signaling pathway between an arthropod parasite and host, where molecules in the blood of a host animal triggers the immunity and development of a ...

It is a previously unknown signalling pathway important for the development of migraine headache, and it might be associated with other headache diseases too,” says Professor Maiken Nedergaard ...

Better understanding of this signalling pathway, through which cell repulsion is controlled, could enable the development of new drugs to combat cancer.