A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

The pathway by which blood cells release the important signalling lipid, sphingosine-1-phosphate (S1P), has now been discovered. They showed that the membrane protein Mfsd2b is responsible for ...

Discovery of cross-species signaling pathway unlocks mysteries around parasite immunity and development Ticks recognize a cytokine from infected mammalian blood, triggering a defense against Lyme ...

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of ...

The mechanism of HH signalling is incomplete, but insight has been gained into the function of lipidation in ligand secretion and transport, as well as into key components of the signalling pathway.