The Detroit Lions and San Francisco 49ers play Monday ... The over/under (point total) is set at 51.5 points. Jeremy Cluff writes: "Every NFL team has injuries, but both of these teams seem ...

While the 49ers have been dealing with injuries all season, they added a key player to the list in last week's loss to the Lions, as quarterback Brock Purdy hurt his right elbow in the closing ...

The Lions achieved a franchise-record 14th win and gained vengeance on their season-ending loss in Santa Clara in last season's NFC Championship with a 40-34 win over the 49ers on Monday night.

With last place in the NFC West clinched, the 49ers know exactly which teams they will face during the 2025 NFL season. The order in which they face them, however, remains to be seen. San ...

The 49ers were officially eliminated from the playoff picture ahead of their Week 16 game against the Dolphins. They failed to qualify for the postseason for the first time since 2020. San ...

And yet you guys managed to bring thoughtfulness — and even some mirth — to this week’s San Francisco 49ers holiday mailbag. Well done! I hope your stockings were full of frankincense and myrrh.

Bo Nix and the Denver Broncos are in the thick of the AFC wild-card race, and the first-round pick has done an admirable job operating Sean Payton's scheme as a rookie quarterback. But something's ...

A rematch of last year's NFC Championship Game, the Detroit Lions vs. San Francisco 49ers was expected to be one of the best games of the season when the schedule was released. Now though ...

It's not the showdown of NFC powers the schedule-makers hoped for back in May, but when the Detroit Lions visit the San Francisco 49ers next Monday night in a rematch of last year's NFC ...

San Francisco 49ers veteran offensive tackle Trent Williams will not play in the final games of the 2024 season. According to NFL Insider Adam Schefter, "49ers HC Kyle Shanahan said LT Trent ...

The Murray State Racers' road trip will continue as they head out to face the Charlotte 49ers on Tuesday ... into this one after the oddsmakers set last week's over/under low at 145, but even ...