UroToday3d
Predicting Response to Bipolar Androgen Therapy (BAT) - A Blood-Based Biomarker Approach
Alicia Morgans interviews Samuel Denmeade about the TRANSFORMER trial and Bipolar Androgen Therapy (BAT) for prostate cancer. Dr. Denmeade explains that the trial, involving 200 patients, compared ...
UroToday4d
Investigating the prognostic utility of GSTP1 promoter methylation in prostate cancer.
We aim to determine the prognostic significance of glutathione S-transferase Pi 1 DNA methylation (mGSTP1) in two independent prostate cancer cohorts with long-term clinical follow-up data. We first ...
UroToday4d
Selective treatment de-escalation in advanced prostate cancer: have we come full circle?
Compelling evidence has solidified the notion of early treatment intensification in managing patients with metastatic hormone-sensitive prostate cancer (mHSPC). Landmark trials have provided Level 1 ...
UroToday4d
Differential expression of metabolic enzymes in testicular germ cell tumors: The impact of glycolytic metabolism in embryonal carcinoma histotype.
Testicular germ cell tumors are the most common solid malignancies in young men, with increasing incidence worldwide. Broadly classified into seminomas and non-seminomas, they exhibit distinct ...
UroToday4d
The effect of tumor downsizing on surgical complexity during nephrectomy after immune checkpoint inhibitors for metastatic renal cell carcinoma.
Immune Checkpoints Inhibitors (ICI) have changed the therapeutic landscape of metastatic renal cell carcinoma first-line treatment with complete response (CR) at metastatic sites observed in 10 to 15% ...
UroToday4d
Incidence and Survival of Patients With Prostate Cancer in North-Rhine Westphalia, Germany.
There is no organized prostate cancer screening in Germany. The aim of this study was to investigate the development of incidence and survival in patients with primary malignant tumors of the prostate ...
UroToday4d
Alternate definitions of adverse pathology to predict a very high risk of metastasis in men with intermediate- and low-risk prostate cancer.
Adverse pathology (AP) is often used as an intermediate end point for long-term outcomes in men with prostate cancer (PCa) who are active surveillance candidates. The association between a commonly ...
UroToday7d
Antibiotic therapy for treating overactive bladder is not supported by clinical evidence.
A number of reports have suggested that the use of prolonged antibiotic treatment could be an effective therapy for patients with overactive bladder (OAB); however, this approach is contrary to ...
UroToday7d
The Association Between Anthropometric Indices and Overactive Bladder (OAB): A Cross-Sectional Study From the NHANES 2005-2018.
The association between different anthropometric indices, including body mass index (BMI), a body shape index (ABSI), lipid accumulation product (LAP), visceral adiposity index (VAI), waist ...
UroToday7d
Risk factors, urodynamic characteristics, and distress associated with nocturnal enuresis in overactive bladder -wet women.
Patients with overactive bladder syndrome-wet (OAB-wet) experience urgency urinary incontinence, particularly urinary frequency and nocturia. Nocturnal enuresis (NE) is less addressed among OAB-wet ...
UroToday7d
Health-promoting lifestyles and influencing factors among pregnant women with urinary incontinence: a multicentre cross-sectional study.
Lifestyle modification is an important part of non-surgical treatment for urinary incontinence (UI) and is strongly recommended. This study aims to explore the status and influencing factors of health ...
UroToday7d
Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy - Beyond the Abstract
Advances in imaging interpretation have led to more accurate risk stratification for men being diagnosed with prostate cancer (PCa). A significant number of men are diagnosed with low-risk prostate ...