Our knowledge of RNA splicing is quite new. Nonetheless, because nearly all eukaryotes have introns and share mechanisms of RNA splicing, splicing itself must be quite ancient. Proponents of the ...

Then the RNA binding protein communicates to the splicing machinery to include or not include ... a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

In most eukaryotic cells, two types of spliceosome ... information—called introns—from the precursors of messenger RNA (pre-mRNA), the molecule responsible for transferring genetic information ...

In contrast, in eukaryotic genes, the primary RNA transcript, known as pre-mRNA, undergoes a process called splicing. During ...