Pacira Announces 104-Week Safety and Efficacy Data Following Local Administration of PCRX-201 for Moderate to Severe Osteoarthritis of the Knee
Participants were broken into two cohorts. The first cohort received one of three doses of PCRX-201. The second cohort received concurrent pretreatment with an intraarticular corticosteroid ...
Ozempic, Wegovy Linked To Lower Hospitalizations In Alcohol Addicts, Research Shows
GLP-1 drugs have been linked to numerous potential health benefits like treatment of existing conditions including heart ...
Medical Xpress3d
The solution to death from a fentanyl overdose could lie in its chemical structure
All of these drugs act at the mu-opioid receptor, which is responsible for their pain relieving properties as well as their addictive and lethal properties. University of Michigan basic science ...
Sparian Biosciences Announces Results from the Phase 1 Clinical Trial of First in Class Novel Arylepoxamide Receptor (AEAr) Agonist Analgesic SBS-1000
SBS-1000 was shown to be safe and well tolerated in healthy volunteers in this Phase 1 Single Ascending Dose (SAD) studyNo ...
Science Daily21h
Exposure to marijuana in the womb may increase risk of addiction to opioids later in life, study finds
Evidence has been growing to suggest that tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, poses risks to the developing fetus by impacting brain development. Now a new ...
News Medical on MSN4d
Canadian guideline expands treatment options for opioid use disorder
An updated evidence-based guideline aimed at helping clinicians and other health care providers manage patients with opioid use disorder recommends buprenorphine and methadone as first-line treatments ...
Ozempic May Curb Alcohol Addiction, New Study Finds: Here's Why
Ozempic can help with blood sugar management, aid with significant weight loss, and perhaps even treat opioid use disorder.
Medscape4d
Attacking Pain At Its Source: New Perspectives on Opioids
targeting of opioid peptide-containing immune cells to peripheral damaged tissue, and gene transfer to enhance opioid production at sites of injury.
Medscape1d
Use of Pure Opioid Antagonists for Management of Opioid-induced Pruritus
Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...
News Medical on MSN3d
MUSC team develops digital toolkit to screen for intimate partner violence and PTSD in opioid use disorder
The opioid crisis has left an estimated 2.5 million people 18 and older in the U.S. with opioid use disorder, or OUD. Despite increased attention to the heavy toll taken by OUD, key risk factors such ...
Neuroscience News21h
Unlocking GABA Receptors
New research has revealed the diverse assembly and regulation of Type-A GABA receptors (GABAARs), which are crucial for ...
Neumora Therapeutics Reports Third Quarter 2024 Financial Results and Provides Business Update
Phase 3 data from KOASTAL-1 study of navacaprant in MDD expected around the end of 2024; KOASTAL-2 and KOASTAL-3 topline data expected in the first half of 2025 Ongoing clinical studies evaluating ...