NFL Combine has come to a close, as many draft-hopeful prospects cemented their draft stock over the weekend headlined by a ...

Jordan Mason and rookie Isaac Guerendo have stepped up admirably in ... "We just don't draft workout warriors. We draft really good football players. But he happens to be a workout warrior ...

After 305 days of working tirelessly on his rehab and fitness, Greenlaw was activated ... San Francisco 49ers running back Isaac Guerendo was nominated for the Pepsi Zero Sugar Rookie of the ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...

The 49ers fear RB Isaac Guerendo suffered an MCL injury against the Cardinals in Week 18. Kyle Shanahan provides several injury updates from the game.

Coach Kyle Shanahan said after Sunday's 47-24 loss to the Cardinals that Guerendo (knee/ankle) likely suffered an MCL sprain and will undergo further testing Monday, Lindsey Pallares of the 49ers' ...

San Francisco 49ers running back Isaac Guerendo is unlikely to play in Sunday's game against the host Miami Dolphins, ESPN reported Thursday. Guerendo is nursing a foot injury sustained in the ...

Guerendo (foot/hamstring) practiced in a limited capacity Friday, Nick Wagoner of ESPN.com reports. Guerendo now has managed back-to-back capped sessions to kick off Week 17 prep as he looks to ...

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of Wednesday's practice with a hamstring injury. He sustained the injury in ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN's Adam Schefter. Guerendo has been limited in practice this week ...

San Francisco 49ers running back Isaac Guerendo. / Bob Kupbens-Imagn Images The San Francisco 49ers are already down Jordan Mason and Christian McCaffrey in their backfield (both are on injured ...

While the San Francisco 49ers injury problems stack up and their list of players on IR balloons to 16, they actually got some good news on running back Isaac Guerendo leading up to their Week 17 ...