Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

A team at UC San Francisco and Gladstone Institutes has developed new drug candidates that show great promise against the ...

Chemists have confirmed a 67-year-old theory about vitamin B1 by stabilizing a reactive molecule in water — a feat long ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...

What is it made of, and what is its function in living things? How do we study the molecular structure of DNA? And why do ...

BenevolentAI has entered a two-year agreement with the MRC Technology to investigate new small molecule and antibody drug candidates. The UK-based artificial intelligence company has teamed up ...

Researchers have produced the most detailed image to date of a bacteriophage -- phage for short -- that has allowed them to see for the first time the structural makeup of the part of the phage that ...

The CAPItello-290 study is comparing the combination of Truqap (capivasertib) with paclitaxel to paclitaxel and placebo as a first-line therapy for patients with inoperable locally advanced or ...