LMW DNA fragmentation. During apoptosis chromatin is cleaved into nucleosomal units; therefore, we can isolate DNA fragments with a size of 200 bp or a multiple thereof from apoptotic cells.

Sakakua C et al examined the histological response, rate of apoptosis, DNA fragmentation and p53 status in tumors from 28 patients with rectal cancer undergoing HCR therapy (combined hyperthermia ...

The terminal stages of programmed cell death (apoptosis) can be identified by the condensation of chromatin and fragmentation of the genomic DNA, alongside blebbing of the membrane. As apoptosis ...

Apoptosis is the mechanism by which defective cells promote their own death to protect the body. It is a complex process, with many stages, in which the different parts of the cell gradually degrade.

George Perry University of Texas at San Antonio; Posted: 26 Feb 2004 DNA Damage Mediated Cell Cycle Reentry in AD The search to elucidate pathologic mechanisms of neuronal death in Alzheimer's disease ...