Apoptosis is the primary mechanism of cell death in tissues with rapid turnover, in which cells are disposed of orderly and engulfed by phagocytic cells to recycle their resources. Apoptosis involves ...

In the classical caspase-dependent apoptosis mechanism (2) found in mammalian cells, active caspase-3/7 cleaves some or all of the DNA-repair protein PARP-1. (11,12) The full-length 116 kDa PARP1 ...

Apoptosis was activated through mitochondria-lost membrane potential, caspase-3 expression and chromatin condensation without DNA damage. G0/G1 and S phases of the cell cycle control were inhibited ...

This shows how, in a fragmentation process, any special pattern of fragment sizes is rapidly washed out — vanishing after a single crumple, in the case of the grid folding.

Apoptosis shows two typical cell changes, it morphologically makes apoptotic bodies by cell shrinkage and chromosomal DNA fragmentation. It is being used as a useful marker for identification of ...

Observing Increases in subG1 Population DNA fragmentation also results in the number of cells stalled at the G1 stage of the cell cycle, and this can be detected using flow cytometry.

Apoptosis, or programmed cell death, is an essential event in many physiological processes as well as in pathological conditions. Western blots were used to measure the expression of several key ...

Walker, P.R., LeBlanc, J. and Sikorska, M. (1997) Evidence that DNA fragmentation in apoptosis is initiated and propagated by single-strand breaks. Cell Death and Differentiation, 4, 506-515.

The aim of this study was to evaluate conventional semen parameters (density, morphology and progressive motility) and the flow-cytometric parameters DNA fragmentation, mitochondrial membrane ...

Methods and Results: Adult rat cardiac myocytes were treated with HSP60, either recombinant human or with HSP60 purified from the media of injured rat cardiac myocytes. ExHSP60 induced apoptosis in ...