For apoptosis, these include chromatin condensation, cell shrinkage and fragmentation, cytochrome c release, caspase activation, cleavage of caspase substrates, cell surface exposure of ...

In this study, bufotalin-induced apoptosis in human hepatocellular carcinoma Hep 3B cells was investigated. The results indicate that externalization of phosphatidylserine, accumulation of sub-G 1 ...

DNA agarose gel electrophoresis The induction of apoptosis by fraction FA-2-b-ß was analyzed by measuring DNA fragmentation. As one of the important hallmarks of apoptosis, DNA fragmentation into ...

This effect is demonstrated by the variable loss of contractile protein seen in patients with heart failure. 28, 29 In addition to containment of activated terminal caspase, DNA fragmentation ...

23andMe has collected genetic data from about 15 million customers. "By filing the lawsuit, the states will be helping ensure that people’s genetic data isn’t misused, exposed in future data breaches, ...

ABSTRACT Varicocele can reduce male fertility potential through various oxidative stress mechanisms. Excessive production of reactive oxygen species may overwhelm the sperm's defenses against ...

While it is known that filament elongation involves end-to-end annealing, the reverse process of filament shortening by fragmentation remains unclear. Here, we use a combination of in vitro ...

Regeneron said Monday it will “prioritize the privacy, security and ethical use” of the personal DNA data from about 15 million people in a $256 million deal to acquire assets of bankrupt ...

Background and Purpose —DNA damage and the DNA repair mechanism are known to be involved in ischemia/reperfusion injury in the brain. The x-ray repair cross-complementing group 1 (XRCC1) protein plays ...

Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear protein that plays key roles in several fundamental cellular processes. PARP-1 catalyzes the polymerization of nicotinamide adenine dinucleotide on ...