Moreover, other factors conspire to make these receptors extraordinarily difficult ... second approach yielded a high-resolution structure (2.3 Å), the lower-resolution structure solved in ...

The FDA has approved Gemtesa® for men with overactive bladder symptoms receiving pharmacological therapy for BPH.

To be included in the study, patients had to have an average of 8 or more micturitions per day, 3 or more urgency episodes per day with or without incontinence, and 2 or more nocturia episodes per ...

Findings suggest targeting neuro-immune pathway could lead to strategies for managing diabetes, obesity or some types of ...

Circulating angiotensinogen (ANG) is synthesized mainly in the liver and cleaved successively by renin and angiotensin-converting enzyme to yield the bioactive peptide angiotensin II (Ang II). Recent ...

It acts through agonist effects on the alpha-2 adrenergic system at both the spinal and supraspinal levels to reduce spasm. Peak plasma levels occur 1 hour after oral administration, with a half ...

It acts by targeting selective alpha 2 adrenergic receptors. It is being developed based on artificial intelligence (AI) approach. It was also under development for the treatment of major depressive ...

Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors; DBH, Dopamine-beta-hydroxylase. Figure 2. Schematic representation of potential pharmacological targets for the treatment of BADs.

Aside from the triggering event, a diagnosis of PTSD requires symptoms in each of five categories: Prazosin blocks responsiveness to norepinephrine, a stress hormone that affects your brain, at ...