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(Most of these details come from Fred Beckey’s seminal “Cascade Alpine Guide: Climbing and High Routes, Vol. 2: Stevens Pass to Rainy Pass,” one of the Bibles of the climbing set. Full of ...

Growth factor signalling is a cell signalling pathway that regulates the growth and development of an organism. Secreted growth factors bind to transmembrane growth factor receptors to stimulate ...

IL-1 activity on both DCs and T cells can further shape the adaptive immune response with variable outcomes. IL-1 signaling in DCs promotes their ability to induce T cell activation, but also direct ...

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The reasons why the cAMP–PKA axis could act as both pro- and anti-inflammatory are similarly poorly understood, but could be a result of a differential balance between other signaling pathways that ...

We believe that the absence of these proteins stimulates several signaling pathways that are related to UPR ... oxidative pathways and mtDNA synthesis 247. RAB7 interacts with mTOR in mouse bone ...

Cover picture: Inspired by the Review by Jung-Soon Mo, Hyun Woo Park and Kun-Liang Guan. Illustrated by Sandra Krahl.