Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual ...

For its part, Twist has been working to further simplify targeted methylation sequencing, making the technique more accessible to scientists of all stripes. Its new NGS Methylation Detection ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

For example, DNA methylation modifies gene expression without altering the nucleotide sequence. A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent ...