Plasma cell leukemia (PCL) is a rare disease that may present de novoor secondary to plasma cell myeloma. Advanced disease and extramedullary involvement are common clinical features at presentation.

Castleman disease is an idiopathic, rare lymphoproliferative disorder. It is classified as multicentric Castleman disease, ...

In a new study, researchers found that the inflammation behind painful episodes in sickle cell disease are correlated with ...

The researchers discovered that disease-scarred lung tissue abounds in plasma cells -- specialized immune cells that typically reside in bone marrow and produce antibodies. "What we found most ...

Two small clinical trials tested the safety of injecting stem cells into the brains of Parkinson's patients and found no ...

PC-CD diagnosis requires interfollicular plasmacytosis, polytypic or occasionally monotypic plasma cells, and exclusion of other conditions such as infections or autoimmune disease.

The abnormal accumulation of antibody-producing immune cells in the lungs may contribute to IPF progression, a new study ...

IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory condition marked by the accumulation of IgG4-positive plasma ...

Somewhere in the body of a patient, a small clump of cells, growing undetected, has begun to form a tumor. It has yet to ...

Having found the plasma cells in lung tissue taken from people who died of IPF, the team began using live mice to see if reducing plasma in the lungs slowed disease formation. This work ...