Researchers at the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) have demonstrated the expanded use of a computational method called the artificial-force-induced reaction (AFIR) ...

Automated reaction path search method predicts accurate stereochemistry of pericyclic reactions using only target molecule structure. Automated reaction path search method predicts accurate ...

Pericyclic reactions, in which electrons move in concert to rearrange a molecule’s structure, are standard tools for synthetic chemists. But examples of such transformations in nature are fairly rare.

Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such ...

Time-resolved imaging of chemically active valence electron densities is a long-sought goal, as these electrons dictate the course of chemical reactions. However, X-ray scattering is always dominated ...

Cycloaddition reactions represent a cornerstone of synthetic organic chemistry, facilitating the formation of cyclic structures through concerted pericyclic processes. Traditionally explained via ...

In chemical reactions, molecules transform from reactants into reaction products through a critical geometry called a transition state that lasts less than one millionth of one millionth of a second.