This article was originally published on www.fansided.com as NFL Week 15 picks and predictions, straight-up and ATS: Bills-Patriots, Packers-Broncos lead huge slate.

The Packers are coming off a last-second win over the Chicago Bears, which thrust them back atop the NFC North and the No. 2 seed in the NFC. They've garnered tons of momentum with that victory, which, if you've been paying attention to the Packers this season, is exactly the time they give it all back with a loss.

With only four weeks remaining in the 2025 NFL season, Bleacher Report's experts are taking big swings to cash in on strong finishes.

My Week 14 straight-up picks went 10-4 and correctly predicted that the Jaguars and Chargers would score upset wins. That moves my straight-up picks to a 73-27 mark over the past seven weeks. Let’s go for an eighth straight week of 10-plus wins in Week 15.

The Packers are coming off a last-second win over the Chicago Bears, wh ich thrust them back atop the NFC North and the No. 2 seed in the NFC. They've garnered tons of momentum with that victory, which, if you've been paying attention to the Packers this season, is exactly the time they give it all back with a loss.

The Houston Texans easily handled the Arizona Cardinals on Sunday afternoon for a 40-20 win at NRG that extended their winning streak to six games and stay in the AFC playoff picture at 9-5. Here are some instant takeaways from the victory.