A consistent loss of motivation can sometimes indicate a mental health condition, such as depression. Some physical health conditions, such as neurological disorders or nutritional deficiencies ...

This pathway senses inflammation and actively suppresses dopamine—a key driver of motivation—resulting in apathy and loss of drive. Blocking the pathway restored motivation, even though the ...

Fatigue and loss of motivation in patients with advanced cancer have long been seen as inevitable side effects of physical decline and weight loss. However, new research from Washington University ...