Our knowledge of RNA splicing is quite new. Nonetheless, because nearly all eukaryotes have introns and share mechanisms of RNA splicing, splicing itself must be quite ancient. Proponents of the ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

In most eukaryotic cells, two types of spliceosome ... information—called introns—from the precursors of messenger RNA (pre-mRNA), the molecule responsible for transferring genetic information ...

Then the RNA binding protein communicates to the splicing machinery to include or not include ... a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often ...

In contrast, in eukaryotic genes, the primary RNA transcript, known as pre-mRNA, undergoes a process called splicing. During ...

An international collaboration has published groundbreaking research, shedding light on the most significant increase in complexity in the history of life's evolution on Earth: the origin of the ...