Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via ...

To characterize the contributions of individual amino acids to the structure or function of ... stabilize the protein by strengthening the interactions between domains. One of the two mutations ...

A joint research team has developed a modular protein adapter technology that enables the stable attachment of various ...

which sometimes results in the expression of a functional protein variant. To circumvent this problem, researchers at Cold Spring Harbor Laboratory (CSHL) designed CRISPR guide RNAs that would mutate ...

Guzikowski et al, Functional specificity of liquid-liquid ... of LLPS complexes was independent of targeted structured ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

The precise relationship between receptor structure and function remains poorly understood. Advances in protein structure ...

Israeli molecular farm startup Polopo is scaling its first sample batch of patatin (potato protein) from genetically modified potatoes to meet the global demand for egg replacements and meat and ...