Mast cells are long-lived, tissue-resident immune cells whose responses are shaped by their anatomical niches. Despite their ...

Mast cells are long‐lived, tissue‐resident immune cells derived from the myeloid lineage and strategically positioned at barrier surfaces such as skin, airways and the gastrointestinal tract. Their ...

First-in-class bispecific antibody designed for mast cell elimination without the safety issues associated with current KIT therapeuticsPhase 1 ...

For patients with unexplained multisystem symptoms, getting answers can mean navigating competing criteria and conflicting ...

Mast cells are centrally implicated in the progression of diabetic kidney disease through their roles in inflammation, fibrotic remodelling and microvascular dysfunction. In the diabetic milieu, ...

Single-cell profiling reveals T-cell changes linked to disease activity and treatment response in childhood eosinophilic ...

Perilla frutescens contains phenolic acids, flavonoids, and other bioactive compounds that show anti-allergic, ...

A recent study published in Science Translational Medicine has examined a new approach to address inflammatory skin diseases, such as dermatitis and rosacea, by focusing on a specific glutamate ...

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study: ...