Studies reporting on patients treated with onabotulinumtoxinA for both upper- and lower-limb spasticity were included in both respective categories of muscles. Some studies had multiple treatment ...

[28] The publication of several further uncontrolled studies on both upper and lower limb spasticity in various disorders followed. In summary, randomized controlled trials evaluating botulinum ...

SL-1002 demonstrated a favorable safety profile in adult patients with limb spasticity, achieving the primary safety endpoint of this first-in-human study. Key secondary efficacy endpoints were ...

If the test does not reveal spasticity, the movements are repeated actively and ... Leg abduction: subject stands up, lower limbs together; examiner throws a ball and subject must abduct a leg to ...