Excitatory transmission in the central nervous system is mediated by the AMPA and NMDA subtypes of glutamate-sensitive receptors. At many central synapses, brief tetanic stimulation of synapses ...
If a larger-than-usual signal exited the slice, that meant LTP had occurred and connections between the neurons in the slice had been strengthened. All you really needed for these experiments were a ...
Full LTP was restored. In brain science, even many successful experiments have vague results that could be read in various ways. Seldom is anything this clear-cut. “It should never have worked,” Lynch ...