Preterm prelabor rupture of membranes (pPROM) is one of the leading causes of preterm birth, occurring in approximately 1% of all pregnancies, and 25% to 30% of preterm births follow pPROM. Although ...

When a pregnant woman's water breaks too early, it often leads to preterm birth, with no effective method to prevent or treat it. Researchers have discovered that the lipid molecule prostacyclin plays ...

Findings in The American Journal of Pathology open avenues for development of therapeutic strategies to enhance membrane repair and prevent preterm birth “Preterm birth is a major challenge in ...

Using a mouse model of fetal membrane rupture, investigators examined the molecular and cellular responses at the rupture site, with a focus on prostaglandin signaling. The most significant finding is ...