Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

Because of its differential affinity for estrogen receptors, genistein has greater activity in bone than in reproductive tissue. Marini et al., therefore, conducted a 2-year randomized trial of ...

Estrogen functions through binding of two different estrogen receptors (ESRs), ESR1 and ESR2 ... via an effect on the RANK/RANKL/OPG signaling pathway (see following section); Enhancing bone ...

Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.