Neurons burdened with fractured DNA may not suffer in silence. They may call for help. That’s the conclusion reached by researchers at MIT’s Picower Institute for Learning and Memory. They discovered ...

We sought to clarify Mre11-dependent processing reactions at DSBs with blocked termini. Blocked DSB ends are created in meiosis by the topoisomerase-like transesterase Spo11 to initiate crossover ...

A new study by researchers in The Picower Institute for Learning and Memory at MIT provides evidence from both mouse models and postmortem human tissue of a direct link between two problems that ...

This study is reported by Dr. Qianwen Sun’s group from Tsinghua University, Dr. Wei Li’s group from Guangzhou Medical University, Dr. Hui Jiang’s group from Peking University Third Hospital, and Wei ...