Disorders of mineral metabolism, including secondary hyperparathyroidism, are thought to contribute to extraskeletal (including vascular) calcification among patients with chronic kidney disease. It ...

Cinacalcet is an effective treatment for secondary hyperparathyroidism in patients on dialysis. Until now, no randomized, placebo-controlled, long-term trial has tested this drug in individuals with ...

AMSTERDAM — In hemodialysis patients with secondary hyperparathyroidism, the calcimimetic cinacalcet improves time to death and cardiovascular (CV) end points, but only in those 65 years and older, a ...

Treatment of secondary hyperparathyroidism with vitamin D and calcium in patients receiving dialysis is often complicated by hypercalcemia and hyperphosphatemia, which may contribute to cardiovascular ...

Exposure to cinacalcet results in increased activation of the CaSR. However, cinacalcet does not directly activate the CaSR—the drug merely sensitizes the receptor to extracellular calcium, and ...

Please provide your email address to receive an email when new articles are posted on . The medical management of mineral and bone disorders in people with end-stage kidney disease on dialysis is ...

Study is the largest to explore this potential safety issue to date. Cinacalcet use does not increase the risk for severe gastrointestinal bleeding that leads to hospitalization or death, according to ...

SAN DIEGO, California — Cinacalcet does not reduce the risk for death or major cardiovascular (CV) events among patients with moderate-to-severe secondary hyperparathyroidism who were on hemodialysis.

In a position statement on cinacalcet use in children on dialysis, the authors emphasized avoiding hypocalcemia. The FDA has not yet approved use of the calcimimetic cinacalcet in children receiving ...

Review the side-effects of Cinacalcet as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the ...

Learn everything you need to know about Cinacalcet-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it. Get up-to-date information on side effects, precautions, warnings, ...

The systematic review carried out by the Assessment Group identified 7 published reports of randomised controlled trials (RCTs) of cinacalcet versus placebo in people with hyperparathyroidism ...