The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

A hybrid modeling framework to optimize Chinese hamster ovary cell cultures for monoclonal antibody (mAb) production reduces the number of modeling parameters needed while returning results that ...

Validated across diverse cell lines and molecule formats, switching to UltraFeed as the fed-batch supplement has enabled titers reaching 10g/L, with peak VCD increases up to 20% and harvest viability ...

High performance cell culture media provide an essential environment to ensure cells are producing high titers and high quality biotherapeutics. These attributes are important drivers in determining ...

Chinese hamster ovary (CHO) cell lines are one of the most-used cell-based protein expression systems for therapeutics, thanks to their ability to support post-translational modifications such as ...