Sending the manual to build the CAS9 enzyme for gene editing The new study describes the use of the LNP technology for Cas9 ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA ...

Its primary component, the Cas9 enzyme (orange), cuts genomic DNA (blue). The enzyme is directed to its target--essentially any sequence along the genome--by hitching it to a strand of guide RNA ...

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from ...

For this reason, compared with all previously available methods, it is much easier to ‘program’ CRISPR-Cas9 at a particular cutting point on the DNA strand. Various types of endonucleases – enzymes ...

“And I am not sure who does.” CRISPR-Cas9 has two components. The first is an enzyme—Cas9—that functions as a cellular scalpel to cut DNA. (In nature, bacteria use it to sever and disarm ...

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA ...

Spanish biotech Integra Therapeutics has upped its arsenal of gene editing tools by licensing Caszyme’s Cas12I nucleases, the ...

Researchers have developed a novel delivery system for sending CRISPR reagents to brain cells, where it performs its gene ...

Second, CRISPR-Cas9 and other DNA editing tools require proteins acquired from certain bacteria to perform the cutting ...