Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA ...

Sending the manual to build the CAS9 enzyme for gene editing The new study describes the use of the LNP technology for Cas9 ...

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from ...

Its primary component, the Cas9 enzyme (orange), cuts genomic DNA (blue). The enzyme is directed to its target--essentially any sequence along the genome--by hitching it to a strand of guide RNA ...

For this reason, compared with all previously available methods, it is much easier to ‘program’ CRISPR-Cas9 at a particular cutting point on the DNA strand. Various types of endonucleases – enzymes ...

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA ...

"It's a completely brand-new type of CRISPR chemistry," says co-first author Christian Baca, a TPCB graduate student in the Marraffini lab. "It's more evidence that CRISPR systems have an array of ...

Spanish biotech Integra Therapeutics has upped its arsenal of gene editing tools by licensing Caszyme’s Cas12I nucleases, the ...

Second, CRISPR-Cas9 and other DNA editing tools require proteins acquired from certain bacteria to perform the cutting ...