The Buffalo Bills injury report for Week 2 is now published.

Buffalo will have its hands full with Detroit during the team's inaugural home opener at the new $2.2 billion stadium on Thursday, and these players will play key roles in the matchup.

Right tackle Blake Miller (knee) and left guard Christian Mahogany (hip) have both been ruled out for the Week 2 matchup. Both players were listed as non-participants for all three days of Detroit’s injury reports this week. The Lions list Larry Borom as Miller’s backup and Miles Frazier as Mahogany’s backup on their unofficial depth chart.