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Alpha-synuclein misfolding as fluid biomarker for Parkinson’s disease measured with the iRS platform
A new fluid biomarker for Parkinson’s disease (PD) was developed, offering a high-accuracy biological classification, ...
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Scientists examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as ...
A new study suggests that targeting the protein alpha-synuclein could be a possible new target for treating melanoma.
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Discovery of α-synuclein's 'fuzzy coat' mechanism offers new insights into Parkinson'sBoth diseases involve Lewy bodies—abnormal clumps of α-synuclein protein in brain cells. Previous research on Lewy bodies has often focused on the rigid core of these fibrils. Now, however, a study by ...
Researchers have identified a key enzyme driving forms of Parkinson’s, and have shown how blocking it restores normal function in animal and cell models – offering a promising new drug target for the ...
"Developing drugs that target alpha-synuclein may be useful in both diseases," said senior author Vivek Unni, M.D., Ph.D., an associate professor of neurology in the OHSU School of Medicine.
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