A new fluid biomarker for Parkinson’s disease (PD) was developed, offering a high-accuracy biological classification, ...

Scientists examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as ...

Both diseases involve Lewy bodies—abnormal clumps of α-synuclein protein in brain cells. Previous research on Lewy bodies has often focused on the rigid core of these fibrils. Now, however, a study by ...

A new study suggests that targeting the protein alpha-synuclein could be a possible new target for treating melanoma.

Researchers have identified a key enzyme driving forms of Parkinson’s, and have shown how blocking it restores normal function in animal and cell models – offering a promising new drug target for the ...

"Developing drugs that target alpha-synuclein may be useful in both diseases," said senior author Vivek Unni, M.D., Ph.D., an associate professor of neurology in the OHSU School of Medicine.