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Scientists examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as ...
Both diseases involve Lewy bodies—abnormal clumps of α-synuclein protein in brain cells. Previous research on Lewy bodies has often focused on the rigid core of these fibrils. Now, however, a study by ...
White arrows indicate accumulation of 18F-SPAL-T-06, suggesting α-synuclein aggregates in the putamen, yellow arrows in the pons, yellow triangle in the cerebellar white matter, and white ...
Parkinson's disease-associated protein alpha-synuclein (αSyn) has demonstrated its involvement in melanoma progression, which represents a dangerous skin cancer type. Medical studies demonstrate ...
"Developing drugs that target alpha-synuclein may be useful in both diseases," said senior author Vivek Unni, M.D., Ph.D., an associate professor of neurology in the OHSU School of Medicine.