The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...
Based on this, they artificially induced the corresponding adenylyl cyclase 2 mutation in mice. As a result, the rodents ...
The compounds identified in these screens are remarkable with respect to their biological activity in mammalian cell-based assays ... screening facility identified a collection of potential adenylyl ...