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F1FO ATP synthase is a critical enzyme for the maintenance of mitochondrial function. Here the authors demonstrate that loss of the F1FO-ATP synthase subunit OSCP and the interaction of OSCP with ...
The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans ...
Bioenergetics: New features of ATP synthase. Science For Life Laboratory. Journal Nature Communications Funder Knut and Alice Wallenberg Foundation (2018.0080), Ragnar Söderberg Foundation (M44 ...
ATP is generated within the matrix by an enzyme called ATP synthase. ... The g-subunit rotates 120o clockwise as a result of the conformation change in bDP-subunit causing the ATP-bE subunit to ...
With no known treatments for mitochondrial diseases or ATP synthase deficiency, the use of muropeptides as an ATP agonist is a significant discovery. Recent advances in the understanding of the ...
ATP synthase CF1 α subunit protein is a key enzyme for energy metabolism in plant kingdom, and plays an important role in multiple cell processes. In this study, the complete atpA gene (accession no.
ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. Researchers have isolated the machines from four fungal species, compared their ...
Since raising the activity of ATP synthase may boost mitochondrial respiration and energy production, a chemical agonist of ATP synthase would have high therapeutic potential in this regard.