The Jacksonville Jaguars (4-12) are 4.5-point underdogs in a road AFC South matchup against the Indianapolis Colts (7-9) on Sunday, January 5, 2025 at Lucas Oil Stadium.NFL odds courtesy of BetMGM

Strangely, vibes are much better on the sidelines of the 4-12 team than the one at 7-9. While a loss is better for the Jaguars' chances at getting a top-five pick — even the first pick is still an outside shot — they are not playing with that mentality. Even if the Colts sneak out a victory here, it will not be by more than five points.

The Indianapolis Colts and Jacksonville Jaguars find themselves in similar predicaments Sunday. Neither will be playing again after Week 18.

The Jaguars now stand at No. 5 in the picking order, with one week of regular season action remaining to determine where teams outside of the postseason picture will select in the first round come April’s 2025 NFL draft.

The Indianapolis Colts and Jacksonville Jaguars complete disappointing seasons at Lucas Oil Stadium. Who ya got?

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between Jacksonville Jaguars and Indianapolis Colts.

Two players are listed on the Jaguars’ final injury report before they face the Colts in Week 18. Here is what you need to know.