The Substance, the new film starring Margaret Qualley and Demi Moore, has set a record for the latter. The body-horror film follows a fading celebrity (played by Moore) who begins to use a black-market drug that creates a younger version of herself (Qualley).

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

With "The Substance," writer-director Coralie Fargeat summarily burns that door to the ground and kicks the ashes around with a gleeful laugh. The independent horror movie builds on themes from classic literature to TikTok influencers to take an unflinching and desperate look at the damage that hating one's body can do,

Coralie Fargeat’s sci-fi shocker follows the downward spiral of a 50-year-old movie star who resorts to drastic measures

Coralie Fargeat’s bloody-as-hell satire lets the star flip the bird to showbiz’s youth obsessions and beauty double standards — in the best (and grossest) way imaginable

Demi Moore’s new film “The Substance” recently received a 13-minute standing ovation at Cannes, proving her worth as one of the most decorated actresses in Hollywood. Moore was also mentioned by Variety and People magazine as a sure nominee for the Oscars 2025.