Louisville is a city in Pottawatomie County, Kansas, United States. As of the 2020 census, the population of the city was 131. Founded in 1857 by Robert Wilson as Rock Post. The area was once part of the Potawatomi Hunting grounds and a large majority of the settlers were either associated with the Pottawatomie Indian Reservation or commerce on the Oregon Trail. Louisville was named for Robert Wilson's son, Louis, and for Louis Vieux, a successful businessman in the area. The town was a contender for county seat of Pottawatomie County but lost to St. George in 1861 and Westmoreland in 1882.
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