Interactions between respiratory syncytial virus and Streptococcus ...
WEBJul 8, 2024 · Lower respiratory tract infections, commonly caused by respiratory syncytial virus (RSV) or Streptococcus pneumoniae (pneumococcus), pose a substantial global health burden, especially in children younger than 5 years of age.
Streptococcus pneumoniae Enhances Human Respiratory Syncytial Virus ...
WEBMay 13, 2015 · Human respiratory syncytial virus (HRSV) and Streptococcus pneumoniae are important causative agents of respiratory tract infections. Both pathogens are associated with seasonal disease outbreaks in the pediatric population, and can often be detected simultaneously in infants hospitalized with bronchiolitis or pneumonia.
Streptococcus pneumoniae’s Virulence and Host Immunity: …
WEBJun 22, 2018 · Streptococcus pneumoniae’s virulence via its polysaccharide capsule is enhanced by its ability to undergo capsule switching (117, 128, 129). Mutations in the capsule polysaccharide synthesis genes (cps) promote serotype switching (117, 128, 129).
WEBJul 8, 2024 · RSV infection afects susceptibility to pneumococcal infection and disease severity by multiple host-dependent and host-independent mechanisms. Epidemiological evidence indicates a synergistic association between yearly epidemics of RSV and pneumococcal pneumonia.
Respiratory Syncytial Virus Increases the Virulence of Streptococcus …
WEBRespiratory syncytial virus (RSV) directly binds to Streptococcus pneumoniae. (A) ELISA showing inhibition of pneumococcus binding to an RSV-coated plate by prior treatment of the plate with an anti-RSV G antibody. Bound pneumococci were detected using an anticapsular polysaccharide antibody.
Respiratory Syncytial Virus and Streptococcus pneumoniae Co ...
WEBRespiratory syncytial virus (RSV) is a common pathogen that causes respiratory tract infection and has been found to co-infect with other bacteria. Although the virus can cause morbidity and mortality in the elderly, RSV-bacteria co-infection had rarely been reported.
Respiratory syncytial virus increases the virulence of Streptococcus …
WEBJul 15, 2014 · Measurements and main results: Following incubation with RSV or purified G protein, pneumococci demonstrated a significant increase in the inflammatory response and bacterial adherence to human ciliated epithelial cultures and markedly increased virulence in a pneumonia model in mice.
Respiratory syncytial virus co-infections might conspire to
WEBSep 27, 2023 · The strongest evidence for the potency of RSV co-infections is in bacterial pneumonia caused by Streptococcus pneumoniae, also called pneumococcus. Many children have pneumococcus bacteria in...
The Pneumococcus–Respiratory Virus Connection—Unexpected …
WEBJun 28, 2022 · Streptococcus pneumoniae is a leading cause of acute respiratory infection and invasive disease in all ages. Nasopharyngeal carriage is a necessary step preceding any pneumococcal disease.
Direct Binding of Respiratory Syncytial Virus to Pneumococci: A ...
WEBDec 1, 2005 · Clinical and epidemiologic data suggest that respiratory syncytial virus (RSV) infections in humans can be complicated by bacterial superinfection e.g., with Streptococcus pneumoniae,...