Tetrodotoxin - Wikipedia
WEBTetrodotoxin (TTX) is a toxin that blocks sodium channels in nerve cells and causes paralysis. It is found in some pufferfish, octopuses, newts, and bacteria, and can be fatal if ingested.
Tetrodotoxin: Biotoxin | NIOSH | CDC - Centers for Disease …
WEBTetrodotoxin is a deadly toxin produced by some puffer fish and other marine animals. It can cause paralysis, respiratory failure, and death if ingested or inhaled. Learn about its properties, symptoms, treatment, and prevention.
Tetrodotoxin Toxicity - StatPearls - NCBI Bookshelf
WEBDec 20, 2023 · Tetrodotoxin is a neurotoxin most commonly found in marine animals. Known for inducing perioral numbness in individuals who consume pufferfish, this toxin poses a unique challenge due to its heat stability, rendering conventional cooking methods ineffective in neutralizing its effects.
Tetrodotoxin - an overview | ScienceDirect Topics
WEBTetrodotoxin (TTX), a highly selective and potent blocker of voltage-dependent sodium channels in motor nerves causes skeletal muscle paralysis and death. It is found in a variety of organisms including the puffer fish, in which its appearance depends on the presence of toxin-synthesizing bacteria.
An Updated Review of Tetrodotoxin and Its Peculiarities
WEBJan 3, 2022 · Tetrodotoxin (TTX) is one of the most potent natural marine toxins, which acts by selectively blocking the action potentials of voltage-gated Na+ channels along nerves, skeletal and cardiac muscle membranes, …
Tetrodotoxin, an Extremely Potent Marine Neurotoxin: …
WEBOct 19, 2015 · Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria …
Tetrodotoxin: History, Biology, and Synthesis - PubMed
WEBDec 16, 2019 · This review provides a comprehensive coverage of the history, biology and chemistry of tetrodotoxin (TTX). It traces the origin of this remarkable molecule all the way back to the ancient Chinese medicine records.
Tetrodotoxin - an overview | ScienceDirect Topics
WEBTetrodotoxin blocks axonal transmission by lowering the conductance of sodium at nodes of Ranvier. It is a selective sodium channel blocker that can block nerve and muscle conduction; action potentials are blocked while resting membrane potentials and resting membrane resistance are not affected.
Tetrodotoxin: Current Biology - Cell Press
WEBOct 10, 2016 · Tetrodotoxin (TTX) is a potent neurotoxin found in various animal groups, especially puffer fishes and newts. Learn about the sources, effects, and functions of TTX in different species and tissues.
Tetrodotoxin: Uses, Interactions, Mechanism of Action
WEBTetrodotoxin is a small molecule that binds to sodium channels and causes paralysis. It is found in the liver and ovaries of some pufferfish and is being investigated for pain and opioid dependence treatment.